Phenylketonuria With Acute Myeloblastic Leukemia in a 9-year-old Boy: Reporting a Rare Case


PATIROĞLU T. , ÜNAL E. , KARDAŞ F. , Ozdemir M. A. , KARAKÜKCÜ M. , Sayilmaz O.

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, cilt.33, 2011

  • Cilt numarası: 33 Konu: 6
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1097/mph.0b013e31821816cf
  • Dergi Adı: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Özet

Phenylketonuria is a genetic metabolic disorder resulting in phenylalanine accumulation in blood. Phenylacetate, which is an abnormal phenylalanine metabolities, was hypothesized to have anticancer activity. Two-years-old boy was diagnosed with classical phenylketonuria because of mental motor retardation. When the patient was 9-year-old, he developed acute myeloblastic leukemia. Here, we present the case with phenylketonuria and acute myeloblastic leukemia because of its extreme rarity.