Obstructive sleep apnoea syndrome is associated with relative hypocortisolemia and decreased hypothalamo-pituitary-adrenal axis response to 1 and 250 mu g ACTH and glucagon stimulation tests

Karaca Z. C., İSMAİLOĞULLARI S., Korkmaz S., Çakır I., Aksu M., Baydemir R., ...More

SLEEP MEDICINE, vol.14, no.2, pp.160-164, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 2
  • Publication Date: 2013
  • Doi Number: 10.1016/j.sleep.2012.10.013
  • Journal Name: SLEEP MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.160-164
  • Keywords: OSAS, HPA axis, ACTH stimulation test, Glucagon stimulation test, Dexamethasone suppression test, Cortisol, AIRWAY PRESSURE THERAPY, OBESE MEN, BLOOD-PRESSURE, CORTISOL, DISORDERS, HORMONE, PROFILE, AGE
  • Erciyes University Affiliated: Yes


Objective: The investigations regarding the effect of obstructive sleep apnoea syndrome (OSAS) on hypothalamo-pituitary-adrenal (HPA) axis revealed conflicting results. We aimed to evaluate the effects of OSAS on HPA-axis with dynamic tests.