Obstructive sleep apnoea syndrome is associated with relative hypocortisolemia and decreased hypothalamo-pituitary-adrenal axis response to 1 and 250 mu g ACTH and glucagon stimulation tests

Karaca, ZÜLEYHA; İSMAİLOĞULLARI, SEVDA; Korkmaz, Selda; Çakır, Ilkay; Aksu, Murat; Baydemir, RECEP; TANRIVERDİ, Fatih; BAYRAM, FAHRİ

doi:10.1016/j.sleep.2012.10.013

Obstructive sleep apnoea syndrome is associated with relative hypocortisolemia and decreased hypothalamo-pituitary-adrenal axis response to 1 and 250 mu g ACTH and glucagon stimulation tests

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Karaca Z. C., İSMAİLOĞULLARI S., Korkmaz S., Çakır I., Aksu M., Baydemir R., ...More

SLEEP MEDICINE, vol.14, no.2, pp.160-164, 2013 (SCI-Expanded)

Publication Type: Article / Article
Volume: 14 Issue: 2
Publication Date: 2013
Doi Number: 10.1016/j.sleep.2012.10.013
Journal Name: SLEEP MEDICINE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.160-164
Keywords: OSAS, HPA axis, ACTH stimulation test, Glucagon stimulation test, Dexamethasone suppression test, Cortisol
Erciyes University Affiliated: Yes

Abstract

Objective: The investigations regarding the effect of obstructive sleep apnoea syndrome (OSAS) on hypothalamo-pituitary-adrenal (HPA) axis revealed conflicting results. We aimed to evaluate the effects of OSAS on HPA-axis with dynamic tests.