Macrocerebellum: Volumetric and Diffusion Tensor Imaging Analysis


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Izbudak I., ACER N. , Poretti A., Gumus K., ZARARSIZ G.

TURKISH NEUROSURGERY, vol.25, no.6, pp.948-953, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 6
  • Publication Date: 2015
  • Doi Number: 10.5137/1019-5149.jtn.11567-14.0
  • Title of Journal : TURKISH NEUROSURGERY
  • Page Numbers: pp.948-953

Abstract

Macrocerebellum is a rare entity characterized by an enlarged cerebellum. We describe a case of a 48-month-old child with macrocerebellum. We performed serial volumetric analysis [total brain volume (TBV) and cerebellar volume] over a period of 4 years. We analyzed the white matter microstructure in the cerebellum using diffusion tensor imaging (DTI). In our patient, we found higher fractional anisotropy (FA) and lower mean diffusivity (MD) in the cerebellar white matter compared to age-matched controls. Our results may represent accelerated myelination secondary to the abnormal cerebellar development.