Macrocerebellum: Volumetric and Diffusion Tensor Imaging Analysis

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Izbudak I., ACER N., Poretti A., Gumus K., ZARARSIZ G.

TURKISH NEUROSURGERY, vol.25, no.6, pp.948-953, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 6
  • Publication Date: 2015
  • Doi Number: 10.5137/1019-5149.jtn.11567-14.0
  • Journal Name: TURKISH NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.948-953
  • Erciyes University Affiliated: Yes

Abstract

Macrocerebellum is a rare entity characterized by an enlarged cerebellum. We describe a case of a 48-month-old child with macrocerebellum. We performed serial volumetric analysis [total brain volume (TBV) and cerebellar volume] over a period of 4 years. We analyzed the white matter microstructure in the cerebellum using diffusion tensor imaging (DTI). In our patient, we found higher fractional anisotropy (FA) and lower mean diffusivity (MD) in the cerebellar white matter compared to age-matched controls. Our results may represent accelerated myelination secondary to the abnormal cerebellar development.