JOURNAL OF INTERNATIONAL ADVANCED OTOLOGY, cilt.13, sa.1, ss.105-109, 2017 (SCI-Expanded)
OBJECTIVE: In patients with a perforated tympanic membrane, topically administered medication reaches the middle ear and thus creates a risk of ototoxicity. The aim of the present study was to evaluate the possible ototoxic effect of the antifungal medication nystatin when administered to the rat middle ear cavity.