Evaluation of coagulation and fibrinolytic parameters in adult onset GH deficiency and the effects of GH replacement therapy: A placebo controlled study


Cakir I. , TANRIVERDİ F. , Karaca Z. C. , KAYNAR L. , ESER B. , ÜNLÜHİZARCI K. , ...Daha Fazla

GROWTH HORMONE & IGF RESEARCH, cilt.22, ss.17-21, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 22 Konu: 1
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.ghir.2011.12.001
  • Dergi Adı: GROWTH HORMONE & IGF RESEARCH
  • Sayfa Sayıları: ss.17-21

Özet

Objective: Increased cardiovascular mortality/morbidity observed in patients with hypopituitarism is ascribed to growth hormone deficiency (GHD) because of its unfavorable cardiovascular risk profile. Abnormalities in the coagulation system may also contribute to increased cardiovascular morbidity/mortality. To get a better insight into the role of hemostasis in GHD we assessed several hemostatic markers at baseline and after 6 months of GH replacement therapy (GHRT).