Evaluation of coagulation and fibrinolytic parameters in adult onset GH deficiency and the effects of GH replacement therapy: A placebo controlled study

Cakir I. , TANRIVERDİ F. , Karaca Z. C. , KAYNAR L. , ESER B. , ÜNLÜHİZARCI K. , ...More

GROWTH HORMONE & IGF RESEARCH, vol.22, no.1, pp.17-21, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 1
  • Publication Date: 2012
  • Doi Number: 10.1016/j.ghir.2011.12.001
  • Title of Journal : GROWTH HORMONE & IGF RESEARCH
  • Page Numbers: pp.17-21


Objective: Increased cardiovascular mortality/morbidity observed in patients with hypopituitarism is ascribed to growth hormone deficiency (GHD) because of its unfavorable cardiovascular risk profile. Abnormalities in the coagulation system may also contribute to increased cardiovascular morbidity/mortality. To get a better insight into the role of hemostasis in GHD we assessed several hemostatic markers at baseline and after 6 months of GH replacement therapy (GHRT).