Therapeutic plasma exchange in patients with thrombotic thrombocytopenic purpura: A retrospective multicenter study

Korkmaz, Serdal; Keklik, MUZAFFER; Sivgin, Serdar; YILDIRIM, Rahşan; Tombak, Anil; Kaya, Mehmet; Acik, Didar; Esen, Ramazan; Hacioglu, Sibel; Sencan, Mehmet; Kiki, Ilhami; Tiftik, Eyup; Kuku, Irfan; Okan, Vahap; Yilmaz, Mehmet; Demir, Cengiz; Sari, Ismail; Altuntas, Fevzi; ÜNAL, ALİ; Ilhan, Osman

doi:10.1016/j.transci.2013.04.016

Therapeutic plasma exchange in patients with thrombotic thrombocytopenic purpura: A retrospective multicenter study

Korkmaz S., Keklik M., Sivgin S., YILDIRIM R., Tombak A., Kaya M. E., ...Daha Fazla

TRANSFUSION AND APHERESIS SCIENCE, cilt.48, sa.3, ss.353-358, 2013 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 48 Sayı: 3
Basım Tarihi: 2013
Doi Numarası: 10.1016/j.transci.2013.04.016
Dergi Adı: TRANSFUSION AND APHERESIS SCIENCE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.353-358
Anahtar Kelimeler: Thrombotic thrombocytopenic purpura, Therapeutic plasma exchange, Fresh frozen plasma, Complete response, HEMOLYTIC-UREMIC SYNDROME, SINGLE-CENTER EXPERIENCE, SYNDROME TTP-HUS, CLEAVING PROTEASE, IMPROVED SURVIVAL, MICROANGIOPATHIES, DEFICIENCY, RITUXIMAB, EFFICACY, STEROIDS
Erciyes Üniversitesi Adresli: Evet

Özet

Thrombotic thrombocytopenic purpura (TIT) is a particular form of thrombotic microangiopathy typically characterized by thrombocytopenia, microangiopathic hemolytic anemia, fever, neurological abnormalities, and renal dysfunction. UP requires a rapid diagnosis and an adapted management in emergency. Daily sessions of therapeutic plasma exchange (TPE) remain the basis of management of UP. Also, UP is a rare disease that is fatal if it is not treated. TPE has resulted in excellent remission and survival rates in UP patients.