Iodine deficiency: a probable cause of neural tube defect

Sarıcı D. , Akın M. A. , Kurtoglu S. , Akın L. , Tucer B. , Yıkılmaz A. , ...More

CHILDS NERVOUS SYSTEM, vol.29, no.6, pp.1027-1030, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 6
  • Publication Date: 2013
  • Doi Number: 10.1007/s00381-013-2038-3
  • Title of Journal : CHILDS NERVOUS SYSTEM
  • Page Numbers: pp.1027-1030


Iodine deficiency is the most devastating event in developing brain in the fetus and neonate. Iodine is absolutely necessary on the myelination, neuronal differentiation, and formation of neural processes, synaptogenesis, and neuronal migration by thyroidal hormones throughout pregnancy and shortly after birth. Neural tube defects (NTD) form after third and fourth gestational weeks and their etiologies are multifactorial.