Does the Presence of Metabolic Syndrome Alter Serum Uric Acid Concentrations, Pain, and Well-Being in Patient with Chronic Musculoskeletal Pain


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TOPRAK ÇELENAY Ş., ÖZER KAYA D., ŞAŞ S.

CLINICAL AND EXPERIMENTAL HEALTH SCIENCES, vol.12, no.4, pp.793-798, 2022 (ESCI) identifier identifier

Abstract

Objective: To compare serum uric acid concentrations, pain and well-being in patients having chronic musculoskeletal pain with and without MetS, and investigate cut-off values. Methods: Patients having chronic musculoskeletal pain with (MetS group, n=48) and without MetS (control group, n=52) were included. The serum uric acid concentration, pain intensity, body composition, physical activity level, quality of life, and psychological status were evaluated by a uric acid blood test, Visual Analogue Scale, Bio-impedance Analyzer, International Physical Activity Questionnaire-7 (IPAQ-7), Nottingham Health Profile, and Hospital Anxiety and Depression Scale, respectively. Results: Uric acid level, fat mass, waist/hip ratio were found higher in the MetS group in comparison to the control group (P<0.05). It was seen that patients in the MetS group had lower physical activity levels than those in the control group (P<0.05). The cut-off points of the uric acid level, fat mass, waist/hip ratio, and physical activity level for detecting MetS were found as 5.25 mg/dl, 37.50 kg, 0.91, and 247.25 METsminutes/week, respectively. Conclusion: Patients with MetS had a greater uric acid level, fat mass, waist/hip ratio, and a lower physical activity level than those without MetS. The increase of uric acid level, fat mass, and waist/hip ratio, and the decrease of physical activity may be critical for patients having musculoskeletal pain with MetS. These results should be considered for the management of these patients.