Akademik Veri Yönetim Sistemi
Abant Tıp Dergisi, cilt.11, sa.1, ss.45-51, 2022 (Hakemli Dergi)
Objective: This study aims to examine the changes between the measurements done in the morning and evening in some acoustic analyses of patients
having myasthenia gravis (MG).
Materials and Methods: Twenty-four MG patients diagnosed with Phase-2A (Mildly Generalized MG) according to the classification of Osserman
and Genkins by a neurology specialist were involved. Videolaryngostroboscopic examinations and acoustic analyses of these patients were performed
in the Ear, Nose, and Throat (ENT) clinic. Perceptual voice assessments were performed using the GRBASI scale, Fo, Shimmer, Jitter, NHR (Noise to
harmonic ratio), MPT (Maximum Phonation Time), and s/z rates were calculated.
Results: When the morning and evening vocal measurements of patients were compared according to the GRBASI scale, a significant difference was
found between B and A and S values, while no statistically significant difference was found between G, R, and I value. Statistically significant
differences were found between cases’ Fo, Shimmer, NHR, s/z Ratio, and VHI (voice handicap index) measurements made in the morning and the
evening. But no difference was found between the Jitter measurements. A statistically significant difference was found between the morning and
evening values of men’s Fo and MPT measurements. Again, a statistically significant difference was found between the morning and evening values
of women’s Fo and MPT measurements.
Conclusion: For Myasthenia Gravis patients, the decrease in muscle power within the day and the tiredness in larynx muscles are an expected process,
and it is objectively presented in this study. In addition, further studies are needed to show that possible communication problems can be prevented
with sound therapies by evaluating the morning and evening acoustic analyses of MG patients.