Investigation of antihypothalamus and antipituitary antibodies in amateur boxers: is chronic repetitive head trauma-induced pituitary dysfunction associated with autoimmunity?


TANRIVERDİ F. , DE BELLIS A., BATTAGLIA M., BELLASTELLA G., BIZZARRO A., SINISI A. A. , ...More

EUROPEAN JOURNAL OF ENDOCRINOLOGY, vol.162, no.5, pp.861-867, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 162 Issue: 5
  • Publication Date: 2010
  • Doi Number: 10.1530/eje-09-1024
  • Title of Journal : EUROPEAN JOURNAL OF ENDOCRINOLOGY
  • Page Numbers: pp.861-867

Abstract

Objective: Current data clearly demonstrate that sports-related chronic repetitive head trauma due to boxing might result in hypopituitarism. However, the mechanism of sports-related traumatic brain injury-induced pituitary dysfunction is still unclear. In order to understand whether autoimmune mechanisms could play a role in the pituitary dysfunction due to sports-related head trauma, we investigated the presence of antipituitary antibodies (APAs) and antihypothalamus antibodies (AHAs) in amateur boxers.