TcR alpha beta-depleted haploidentical transplantation results in adult acute leukemia patients


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Kaynar L. , Demir K., Turak E. E. , OZTURK C. P. , ZARARSIZ G. , GÖNEN Z. B. , ...More

HEMATOLOGY, vol.22, no.3, pp.136-144, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.1080/10245332.2016.1238182
  • Title of Journal : HEMATOLOGY
  • Page Numbers: pp.136-144
  • Keywords: alpha beta T cell depletion, haploidentical transplantation, immune reconstitution, STEM-CELL TRANSPLANTATION, TOTAL-BODY IRRADIATION, VERSUS-HOST-DISEASE, MARROW, STRATEGIES, DONORS

Abstract

Introduction: The use of alpha beta+ T-cell-depleted grafts is a novel approach to prevent graft failure, graft-versus-host disease (GVHD), and non-relapse mortality (NRM) in patients undergoing haploidentical hematopoietic stem cell transplantation.