The different doses of radiation therapy-induced damage to the ovarian environment in rats


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ÖNDER G. Ö., BALCIOĞLU E., BARAN M., CEYHAN A., cengiz Ö., alişan suna p., ...More

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, vol.97, no.3, pp.367-375, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 97 Issue: 3
  • Publication Date: 2021
  • Doi Number: 10.1080/09553002.2021.1864497
  • Journal Name: INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.367-375
  • Keywords: Radiation, ovary, pro-inflammatory cytokines, apoptosis
  • Erciyes University Affiliated: Yes

Abstract

Purpose: The sequelae of premature loss of ovarian function can undoubtedly have undesirable effects for a woman although radiotherapy is one of the most relevant treatment modalities for various types of malignancies. The aim of this study was to determine the effect of different doses of radiation on ovarian folliculogenesis, inflammation, and apoptotic markers.