Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials


Bhala N., Emberson J., Merhi A., Abramson S., Arber N., Baron J. A. , ...Daha Fazla

LANCET, cilt.382, ss.769-779, 2013 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 382 Konu: 9894
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/s0140-6736(13)60900-9
  • Dergi Adı: LANCET
  • Sayfa Sayıları: ss.769-779

Özet

Background The vascular and gastrointestinal effects of non-steroidal anti-inflammatory drugs (NSAIDs), including selective COX-2 inhibitors (coxibs) and traditional non-steroidal anti-inflammatory drugs (tNSAIDs), are not well characterised, particularly in patients at increased risk of vascular disease. We aimed to provide such information through meta-analyses of randomised trials.