Comparison of in vitro activities of antifungal drugs and ethanolic extract of propolis against Trichophyton rubrum and T-mentagrophytes by using a microdilution assay

KOC, AN; Silici, SİBEL; AYANGIL, Demet; FERAHBAS, A; Çankaya, S

doi:10.1111/j.1439-0507.2005.01128.x

Comparison of in vitro activities of antifungal drugs and ethanolic extract of propolis against Trichophyton rubrum and T-mentagrophytes by using a microdilution assay

Atıf İçin Kopyala

KOC A., Silici S. , AYANGIL D. , FERAHBAS A., Çankaya S.

MYCOSES, cilt.48, sa.3, ss.205-210, 2005 (SCI İndekslerine Giren Dergi)

Cilt numarası: 48 Konu: 3
Basım Tarihi: 2005
Doi Numarası: 10.1111/j.1439-0507.2005.01128.x
Dergi Adı: MYCOSES
Sayfa Sayıları: ss.205-210

Özet

The in vitro activities of propolis against 29 strains of dermatophytes were compared with those of terbinafine, itraconazole, ketoconazole, and fluconazole. Minimal inhibitory concentrations (MICs) were determined according to a National Committee for Clinical Laboratory Standards broth microdilution method. Among the systemic antifungals tested, terbinafine was the most potent. Propolis showed important antifungal activity and it merits further investigation as a potentially useful agent for the treatment of dermatophytosis.