Copy For Citation
ENGELHARDT K. R., GERTZ M. E., KELES S., SCHAEFFER A. A., SIGMUND E. C., GLOCKER C., ...More
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, vol.136, no.2, pp.402-412, 2015 (SCI-Expanded)
-
Publication Type:
Article / Article
-
Volume:
136
Issue:
2
-
Publication Date:
2015
-
Doi Number:
10.1016/j.jaci.2014.12.1945
-
Journal Name:
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
-
Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
-
Page Numbers:
pp.402-412
-
Keywords:
Primary combined immunodeficiency, hyper-IgE syndrome, autosomal recessive hyper-IgE syndrome, dedicator of cytokinesis 8, signal transducer and activator of transcription 3, Molluscum contagiosum, HYPER-IGE SYNDROME, BONE-MARROW-TRANSPLANTATION, STEM-CELL TRANSPLANTATION, DOCK8 DEFICIENCY, MUTATIONS, IMMUNODEFICIENCY, STAT3, GLYCOSYLATION, DISORDER, SURVIVAL
-
Erciyes University Affiliated:
Yes
Abstract
Background: Mutations in dedicator of cytokinesis 8 (DOCK8) cause a combined immunodeficiency (CID) also classified as autosomal recessive (AR) hyper-IgE syndrome (HIES). Recognizing patients with CID/HIES is of clinical importance because of the difference in prognosis and management.