Chronic occupational lead exposure and thyroid function
JOURNAL OF TRACE ELEMENTS IN EXPERIMENTAL MEDICINE, cilt.12, sa.1, ss.45-49, 1999 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 12 Sayı: 1
- Basım Tarihi: 1999
- Doi Numarası: 10.1002/(sici)1520-670x(1999)12:1<45::aid-jtra5>3.0.co;2-d
- Dergi Adı: JOURNAL OF TRACE ELEMENTS IN EXPERIMENTAL MEDICINE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
- Sayfa Sayıları: ss.45-49
- Anahtar Kelimeler: lead exposure, thyroid function, occupational exposure, INORGANIC LEAD
- Erciyes Üniversitesi Adresli: Evet
Özet
Thyroid function was studied in 27 male workers occupationally exposed to lead. The mean blood lead concentration of the workers was 17.07 mu g/dl [standard deviation (SD) 8.96, range 6-36]. The mean and SD duration of lead exposure was 16.70 and 5.38 (range 1-22) years. The total thyroxine (T4), free thyroxine (FT4), total triiodothyronine (T3), free triiodothyronine (FT3), and thyrotropin [thyroid-stimulating hormone (TSH)] concentrations in serum showed an increase compared with the normal values of the Kayseri population (n = 30). However, these values were in the "normal" range of the Kayseri population and Amerlex Firm. In regression equations, the duration of lead exposure and age had a weak but significant association with T4. (C) 1999 Wiley-Liss, Inc.