Evaluation of the effects of intra-arterial sugammadex and dexmedetomidine: an experimental study

Hanci, Volkan; Ozbilgin, Sule; Ozbal, Seda; Kamaci, GONCA; Ates, Hasan; Boztas, Nilay; Ergur, Bekir; Arikanoglu, Ahmet; Yilmaz, Osman; Yurtlu, Bulent

doi:10.1016/j.bjane.2015.01.003

Evaluation of the effects of intra-arterial sugammadex and dexmedetomidine: an experimental study

Hanci V., Ozbilgin S., Ozbal S., Kamaci G., Ates H., Boztas N., ...More

REVISTA BRASILEIRA DE ANESTESIOLOGIA, vol.66, no.5, pp.456-464, 2016 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 66 Issue: 5
Publication Date: 2016
Doi Number: 10.1016/j.bjane.2015.01.003
Journal Name: REVISTA BRASILEIRA DE ANESTESIOLOGIA
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.456-464
Keywords: Sugammadex, Dexmedetomidine, Intra-arterial, Rabbit, Experimental
Erciyes University Affiliated: No

Abstract

Background: Intra-arterial injection of medications may cause acute and severe ischemia and result in morbidity and mortality. There is no information in the literature evaluating the arterial endothelial effects of sugammadex and dexmedetomidine. The hypothesis of our study is that sugammadex and dexmedetomidine will cause histological changes in arterial endothelial structure when administered intra-arterially.