Antioxidant potential of propylthiouracil in patients with psoriasis

Utaş S., Kose K., Yazici C., Akdas A., Kelestimur F.

CLINICAL BIOCHEMISTRY, vol.35, no.3, pp.241-246, 2002 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 3
  • Publication Date: 2002
  • Doi Number: 10.1016/s0009-9120(02)00294-1
  • Journal Name: CLINICAL BIOCHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.241-246
  • Erciyes University Affiliated: Yes

Abstract

Objective: There is growing evidence supporting the reactive oxygen species (ROS) in the pathogenesis of psoriasis. Propylthiouracil (PTU), an antithyroid drug, has been shown to have beneficial effects on psoriasis. The aim of this study was to investigate both disturbances in oxidant/antioxidant system in psoriasis and whether PTU, shown to have immunomodulatory effects and antioxidant potential. has effects on oxidant/antioxidant system and clinical improvement in psoriatics.