Akademik Veri Yönetim Sistemi
Sağlık Bilimleri Dergisi, cilt.33, sa.1, ss.25-34, 2024 (Hakemli Dergi)
The purpose of this study was to compare the amounts of serum amyloid a, haptoglobin, fibrinogen, and periostin in calves with respiratory system disease complex before and after treatment. Three groups were used in the study: an acute group (n=10) made up of calves with acute respiratory system disease complex symptoms, a chronic group made up of calves with chronic respiratory system disease complex symptoms, and a control group made up of disease-free, healthy calves. Before and after therapy (day 0, 7 and 14), clinical examinations were performed and blood samples were taken from the acute and chronic groups. Calves in the control group only had one clinical evaluation and blood sample collection. Results showed that both the acute and chronic groups exhibited clinical improvement after treatment. Before treatment, the concentrations of fibrinogen, serum amyloid A, and haptoglobin in the acute and chronic groups were significantly higher than those in the control group (p<0.001). On days 7 and 14, the serum periostin concentrations of the acute group were lower than those of the chronic group and control group (p<0.05). However, no significant difference was observed in serum periostin concentrations before and after treatment in both the acute and chronic groups (p>0.05). Additionally, a positive correlation was found between the respiratory system disease complex scores and the concentrations of serum amyloid A, haptoglobin, and fibrinogen. However, there was no significant correlation between periostin concentrations and respiratory system disease complex scores, as well as between fibrinogen, haptoglobin, and serum amyloid A concentrations (p>0.05).Based on the findings, it can be concluded that haptoglobin, serum amyloid A, and fibrinogen values, rather than periostin, play an important role in supporting the diagnosis and prognosis of respiratory system disease complex in calves.