Consistent supramolecular motifs and different local symmetries in the structures of 2-amino-5-(4-fluorophenyl)-1,3-thiazole-4-carbaldehyde and 2-amino-5-(4-chlorophenyl)-1,3-thiazole-4-carbaldehyde

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Guseinov F. I., Afanaseva K. A., Gaidar S. M., Pikina A. M., AKKURT M., Aliyeva F. S., ...Daha Fazla

Acta Crystallographica Section E: Crystallographic Communications, cilt.82, ss.14-18, 2026 (ESCI, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 82
• Basım Tarihi: 2026
• Doi Numarası: 10.1107/s2056989025010667
• Dergi Adı: Acta Crystallographica Section E: Crystallographic Communications
• Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
• Sayfa Sayıları: ss.14-18
• Anahtar Kelimeler: 1,3-thiazole ring, crystal structure, haloketones, halooxiranes
• Erciyes Üniversitesi Adresli: Evet

Özet

The first title compound, C10H7FN2OS, crystallizes in space group P1 with two independent molecules in the asymmetric unit, which form a dimer with an R22(8) motif through pairwise N - H⋯N hydrogen bonds. In the crystal of (I), N - H⋯O hydrogen bonds bind the dimers into zigzag ribbons running along the [100] direction, generating R44(14) motifs. The second title compound, C10H7ClN2OS (space group I2/a), contains one molecule in the asymmetric unit, which forms a dimer with an R22(8) motif via inversion symmetry. In the extended structure, the molecules form zigzag ribbons in the [100] direction by N - H⋯N and N - H⋯O hydrogen bonds, resulting in consecutive R41(8)R21(5)R22(8)R21(5)R41(8) motifs. The Hirshfeld surface analyses of the compounds (I) and (II) indicates that the most important factors influencing the crystal packing are H⋯H interactions [21.1% for molecule A of (I), 20.3% for molecule B of (I) and 21.0% for (II)].