Gemcitabine Alone versus combination of Gemcitabine and Cisplatin for the Treatment of Patients with Locally Advanced and/or Metastatic Pancreatic Carcinoma: A Retrospective Analysis of multicenter study

Inal, A.; Kos, F.; Algin, E.; Yildiz, Rıfat; Dikiltas, M.; Unek, I.; Colak, DURSUN; Elkiran, E.; Helvaci, K.; Geredeli, C.; Dane, F.; Balakan, O.; Kaplan, M.; Durnali, A.; Harputoglu, H.; Goksel, G.; Ozdemir, Nalan; Buyukberber, S.; Gumus, MUSTAFA; Kucukoner, M.; ÖZKAN, METİN; Uncu, D.; Benekli, M.; Isikdogan, A.

doi:10.4149/neo_2012_038

Gemcitabine Alone versus combination of Gemcitabine and Cisplatin for the Treatment of Patients with Locally Advanced and/or Metastatic Pancreatic Carcinoma: A Retrospective Analysis of multicenter study

Atıf İçin Kopyala

Inal A., Kos F. T., Algin E., Yildiz R., Dikiltas M., Unek I. T., ...Daha Fazla

NEOPLASMA, cilt.59, sa.3, ss.297-301, 2012 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 59 Sayı: 3
Basım Tarihi: 2012
Doi Numarası: 10.4149/neo_2012_038
Dergi Adı: NEOPLASMA
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.297-301
Erciyes Üniversitesi Adresli: Evet

Özet

The majority of patients with pancreatic cancer is of advanced disease. Several randomized Phase II and III trials suggest that the combination of gemcitabine and cisplatin (GemCis) response rates were higher than Gemcitabine (Gem) alone, however the trials were not enough powered to indicate a statistically significant prolongation of survival in patients with advanced pancreatic adenocarcinoma. The aim of this retrospective multicenter study is to evaluated the efficiency of Gem alone versus GemCis in patients with locally advanced and/or metastatic pancreatic adenocarcinoma.