Determination of the effect of fluconazole against Candida albicans and Candida glabrata by using microbroth kinetic assay

Kaya E., Ozbilge H.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.42, sa.2, ss.325-328, 2012 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42 Sayı: 2
  • Basım Tarihi: 2012
  • Doi Numarası: 10.3906/sag-1010-1211
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.325-328
  • Erciyes Üniversitesi Adresli: Evet

Özet

Aim: To evaluate the antifungal activity of a model antifungal (fluconazole) against Candida albicans (ATCC 90028) and Candida glabrata (RSKK 04019) strains using a microbroth kinetic assay based on continuous monitoring of changes in the optical density of fungal growth. Recently, antifungal susceptibility testing has become more important because of the increasing incidence of both fungal infections and antifungal drug resistance.