Rubella-associated hemophagocytic syndrome in an infant
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, cilt.27, sa.8, ss.430-431, 2005 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 27 Sayı: 8
- Basım Tarihi: 2005
- Doi Numarası: 10.1097/01.mph.0000177427.94164.df
- Dergi Adı: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.430-431
- Anahtar Kelimeler: rubella, hemophagocytic syndrome, leukoerythrophagocytosis, infant
- Erciyes Üniversitesi Adresli: Evet
Özet
Hemophagocytic syndrome (HPS) is a fulminant disorder characterized pathologically by multiple-organ infiltration of hemophagocytic histiocytes in the lymphoreticular tissues. The characteristic pathologic feature is reactive histiocytic hyperplasia with leukoerythrophagocytosis in a variety of organs. This disorder occurs most often in patients in whom the immune system is compromised and has been associated with a variety of infectious agents, including viruses, bacteria, mycobacteria, spirochetes, fungi, and parasites. The authors describe a 2.5-month-old girl with rubella-associated HPS, demonstrated by postmortem liver necropsy.