Evaluation of the efficacy and safety of original filgrastim (Neupogen (R)), biosimilar filgrastim (Leucostim (R)) and Lenograstim (Granocyte (R)) in CD34(+) peripheral hematopoietic stem cell mobilization procedures for allogeneic hematopoietic stem cell transplant donors


Sivgin S., Karakuş E., Keklik M., ZARARSIZ G., Solmaz M., Kaynar L., ...More

TRANSFUSION AND APHERESIS SCIENCE, vol.54, no.3, pp.410-415, 2016 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 54 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.1016/j.transci.2016.03.003
  • Journal Name: TRANSFUSION AND APHERESIS SCIENCE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.410-415
  • Keywords: Allogeneic hematopoietic stem cell transplantation, Stem cell mobilization, G-CSF, Biosimilars
  • Erciyes University Affiliated: Yes

Abstract

Objectives and Aim: In this study, we aimed to compare the potency of different G-CSF agents including original filgrastim (Neupogen (R)), biosimilar filgrastim (Leucostim (R)) and Lenograstim (Granocyte (R)) on CD34(+) cell mobilization in patients that underwent allogeneic hematopoietic stem cell transplantation (alloHSCT).