Comparison of serum NO, TNF-alpha, IL-1 beta, sIL-2R, IL-6 and IL-8 levels with grades of retinopathy in patients with diabetes mellitus

Doganay, S; Evereklioglu, CEM; Er, H; Turkoz, Y; Sevinc, A; Mehmet, Nihayet; Savli, H

doi:10.1038/sj.eye.6700095

Comparison of serum NO, TNF-alpha, IL-1 beta, sIL-2R, IL-6 and IL-8 levels with grades of retinopathy in patients with diabetes mellitus

Atıf İçin Kopyala

Doganay S., Evereklioglu C., Er H., Turkoz Y., Sevinc A., Mehmet N., ...Daha Fazla

EYE, cilt.16, sa.2, ss.163-170, 2002 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 16 Sayı: 2
Basım Tarihi: 2002
Doi Numarası: 10.1038/sj.eye.6700095
Dergi Adı: EYE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.163-170
Erciyes Üniversitesi Adresli: Evet

Özet

Background Vitreal interleukin (IL)-1beta (IL-1beta), IL-6, IL-8, tumor necrosis factor-alpha (TNF-alpha) and nitric oxide (NO) levels have previously been determined in patients with proliferative diabetic retinopathy (PDR). However, at present there is no cohort study linking serum levels of NO and many inflammatory cytokines such as TNF-alpha, IL-1beta, soluble IL-2 receptor (sIL-2R), IL-6 and IL-8 to the grade of the microvascular complications.