Comparison of serum NO, TNF-alpha, IL-1 beta, sIL-2R, IL-6 and IL-8 levels with grades of retinopathy in patients with diabetes mellitus


Doganay S., Evereklioglu C. , Er H., Turkoz Y., Sevinc A., Mehmet N. , ...Daha Fazla

EYE, cilt.16, ss.163-170, 2002 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 16 Konu: 2
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1038/sj.eye.6700095
  • Dergi Adı: EYE
  • Sayfa Sayıları: ss.163-170

Özet

Background Vitreal interleukin (IL)-1beta (IL-1beta), IL-6, IL-8, tumor necrosis factor-alpha (TNF-alpha) and nitric oxide (NO) levels have previously been determined in patients with proliferative diabetic retinopathy (PDR). However, at present there is no cohort study linking serum levels of NO and many inflammatory cytokines such as TNF-alpha, IL-1beta, soluble IL-2 receptor (sIL-2R), IL-6 and IL-8 to the grade of the microvascular complications.