Unicentric Castleman's disease associated with end stage renal disease caused by amyloidosis


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EROĞLU E. , KOÇYİĞİT I. , ÜNAL A. , SİPAHİOĞLU M. H. , AKGÜN H. , KAYNAR L. , ...More

WORLD JOURNAL OF CLINICAL CASES, vol.5, no.3, pp.119-123, 2017 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 5 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.12998/wjcc.v5.i3.119
  • Title of Journal : WORLD JOURNAL OF CLINICAL CASES
  • Page Numbers: pp.119-123

Abstract

Castleman's disease (CD), also known as angiofolicular lymph node hyperplasia, is a rare heterogenous group of lymphoproliferative disorders. Histologically, it can be classified as hyaline vascular type, plasma cell type, or mixed type. Clinically two different subtypes of the CD are present: Unicentric and multicentric. Unicentric CD is generally asymptomatic and associated with hyaline vascular type, and its diagnoses depend on the localized lymphadenopathy on examination or imaging studies. However, multicentric CD presents with generalized lym-phadenopathy and systemic symptoms including malaise, fever, night sweats, weight loss, and it is associated with the plasma cell type and mix type. Herein, we report a patient with unicentric CD of the plasma cell type without systemic symptoms, who developed end stage renal failure caused by amyloidosis 6 years after onset of CD.