Unicentric Castleman's disease associated with end stage renal disease caused by amyloidosis


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EROĞLU E. , KOÇYİĞİT I. , ÜNAL A. , SİPAHİOĞLU M. H. , AKGÜN H. , KAYNAR L. , ...Daha Fazla

WORLD JOURNAL OF CLINICAL CASES, cilt.5, ss.119-123, 2017 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 5 Konu: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.12998/wjcc.v5.i3.119
  • Dergi Adı: WORLD JOURNAL OF CLINICAL CASES
  • Sayfa Sayıları: ss.119-123

Özet

Castleman's disease (CD), also known as angiofolicular lymph node hyperplasia, is a rare heterogenous group of lymphoproliferative disorders. Histologically, it can be classified as hyaline vascular type, plasma cell type, or mixed type. Clinically two different subtypes of the CD are present: Unicentric and multicentric. Unicentric CD is generally asymptomatic and associated with hyaline vascular type, and its diagnoses depend on the localized lymphadenopathy on examination or imaging studies. However, multicentric CD presents with generalized lym-phadenopathy and systemic symptoms including malaise, fever, night sweats, weight loss, and it is associated with the plasma cell type and mix type. Herein, we report a patient with unicentric CD of the plasma cell type without systemic symptoms, who developed end stage renal failure caused by amyloidosis 6 years after onset of CD.