The Serum YKL-40 Level is Associated with Vascular Injury and Predicts Proteinuria in Nephrotic Syndrome Patients

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Kocyigit I., Gungor O., Dogan E., Karadavut S., Karakukcu C., EROĞLU E., ...More

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, vol.22, no.3, pp.257-264, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.5551/jat.26385
  • Journal Name: JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.257-264
  • Keywords: Nephrotic syndrome, YKL-40, Vascular injury, Proteinuria, CORONARY-ARTERY-DISEASE, CARDIOVASCULAR-DISEASE, DIABETES-MELLITUS, BIOMARKER, MORTALITY, CHILDREN, ATHEROSCLEROSIS
  • Erciyes University Affiliated: Yes

Abstract

Aim: Nephrotic syndrome (NS) is associated with an increased rate of cardiovascular events. The YKL-40 level is associated with atherosclerosis, endothelial dysfunction and proteinuria in renal and non-renal populations. The aim of this study was to investigate the relationships between the YKL-40 level and both vascular injury and proteinuria in NS patients.