<i>Cryptococcus</i><i> neoformans</i> fungemia in a liver transplant patient: Case report and literature review

Evren K., Mutlu-Sariguzel F., KOÇ A. N.

JOURNAL OF INFECTION AND CHEMOTHERAPY, cilt.31, sa.2, 2025 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 31 Sayı: 2
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1016/j.jiac.2024.08.011
  • Dergi Adı: JOURNAL OF INFECTION AND CHEMOTHERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE
  • Anahtar Kelimeler: Cryptococcus neoformans, Fungemia, Solid organ transplantation recipients
  • Erciyes Üniversitesi Adresli: Evet

Özet

Cryptococcus neoformans is an environmental fungus that can frequently cause life-threatening meningitis and fungemia in acquired immunodeficiency syndrome patients. In recent years, cases of these fungal infections are increasingly identified in HIV-negative patients especially in solid organ transplantation (SOT) patients. Cryptococcal fungemia can often clinically present as life-threatening disseminated disease from subclinical colonization. This is a factor that affects survival, especially in patients with decompensated liver cirrhosis and SOT recipients. Early diagnosis and appropriate treatment are important for the course of the disease. This report describes the cryptococcal fungemia that developed in an HIV-negative patient after SOT due to alcohol-related liver cirrhosis.