Efficient synthesis of some oxalacetic acid and pyruvic acid derivatives from the reactions of 2,3-furandiones with 2-phenylindole

Sener A., Mengeş N., AKKURT M. , Karaca S., Bueyuekguengoer O.

TETRAHEDRON LETTERS, vol.49, no.17, pp.2828-2831, 2008 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 17
  • Publication Date: 2008
  • Doi Number: 10.1016/j.tetlet.2008.02.118
  • Title of Journal : TETRAHEDRON LETTERS
  • Page Numbers: pp.2828-2831


Oxalacetic acid and pyruvic acid derivatives have been synthesized efficiently in high yields by the treatment of 4-ethoxycarbonyl-5phenyl-2,3-furandione and 4-benzoyl-5-phenyl-2,3-furandione with 2-phenylindole at room temperature and converted to simple derivatives such as an ester or a hydrazone. (C) 2008 Elsevier Ltd. All rights reserved.