Usefulness of C-reactive protein/albumin ratio as a predictor of new-onset atrial fibrillation in SARS coronavirus-2


KELEŞOĞLU Ş., Yilmaz Y., Ozkan E., Calapkorur B., Dursun Z. B., ULU KILIÇ A., ...More

BIOMARKERS IN MEDICINE, vol.15, no.13, pp.1167-1176, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 13
  • Publication Date: 2021
  • Doi Number: 10.2217/bmm-2020-0866
  • Journal Name: BIOMARKERS IN MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core, EMBASE, MEDLINE
  • Page Numbers: pp.1167-1176
  • Keywords: C-reactive protein, albumin ratio, new-onset atrial fibrillation, SARS-CoV-2
  • Erciyes University Affiliated: Yes

Abstract

Aim: To investigate whether C-reactive protein/albumin ratio (CAR) has an association with new onset atrial fibrillation (NOAF) in SARS-CoV-2. Materials & methods: This study included 782 patients with SARS-CoV-2 infection, who were hospitalized in Turkey. The end point of the study was an occurrence of NOAF. Results: NOAF was identified in 41 patients (5.2%). Subjects who developed NOAF had a higher CAR compared with those who did not develop NOAF (p < 0.001). In the multivariate logistic regression analysis the CAR (odds ratio = 2.879; 95% CI: 1.063-7.793; p = 0.037) was an independent predictor of NOAF. Conclusion: A high level of CAR in blood samples is associated with an increased risk of developing NOAF in SARS-CoV-2.