The effects of dexmedetomidine on mesenteric arterial occlusion-associated gut ischemia and reperfusion-induced gut and kidney injury in rabbits


Kilic K., Hanci V., Selek S., Sozmen M., Kilic N., Citil M., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.178, sa.1, ss.223-232, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 178 Sayı: 1
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.jss.2012.03.073
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.223-232
  • Anahtar Kelimeler: Experimental mesenteric ischemia, Dexmedetomidine, Renal, Intestinal, Rabbit, Mesenteric artery occlusion, INTESTINAL ISCHEMIA/REPERFUSION INJURY, CRITICALLY-ILL PATIENTS, INFLAMMATORY RESPONSES, CEREBRAL-ISCHEMIA, GLOBAL-ISCHEMIA, NITRIC-OXIDE, ALPHA-2-ADRENOCEPTOR AGONIST, SUPEROXIDE-DISMUTASE, RAT-KIDNEY, MODEL
  • Erciyes Üniversitesi Adresli: Hayır

Özet

Objective: We assessed the antioxidant activity of dexmedetomidine (Dex) administered during the ischemic period in a rabbit model of mesenteric ischemia/reperfusion (I/R) injury using biochemical and histopathological methods.