Decreased nitric oxide production in primary open-angle glaucoma


Doganay S., Evereklioglu C., Turkoz Y., Er H.

EUROPEAN JOURNAL OF OPHTHALMOLOGY, cilt.12, sa.1, ss.44-48, 2002 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 1
  • Basım Tarihi: 2002
  • Dergi Adı: EUROPEAN JOURNAL OF OPHTHALMOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.44-48
  • Erciyes Üniversitesi Adresli: Hayır

Özet

PURPOSE. Raised intraocular pressure (IOP) is the major risk factor responsible for optic nerve damage in primary open-angle glaucoma (POAG). The trabecular meshwork acts as a valve in aqueous outflow and relaxes with nitric oxide (NO) agonists. Since NO is synthesized by endothelium and smooth muscle elsewhere in the body, this study investigated the NO levels in the aqueous humor of patients with POAG compared with cataract patients.