Rapamycin has a beneficial effect on controlling epilepsy in children with tuberous sclerosis complex: results of 7 children from a cohort of 86

CANPOLAT M., PER H., GÜMÜŞ H., Yikilmaz A., ÜNAL E., PATIROĞLU T., ...Daha Fazla

CHILDS NERVOUS SYSTEM, cilt.30, sa.2, ss.227-240, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s00381-013-2185-6
  • Dergi Adı: CHILDS NERVOUS SYSTEM
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.227-240
  • Anahtar Kelimeler: Children, Epilepsy, Rapamycin, Tuberous sclerosis complex, GIANT-CELL ASTROCYTOMA, MAMMALIAN TARGET, SIGNALING PATHWAY, PHARMACOLOGICAL INHIBITION, CONSENSUS CONFERENCE, INFANTILE SPASMS, NATURAL-HISTORY, MTOR PATHWAY, MOUSE MODEL, VIGABATRIN
  • Erciyes Üniversitesi Adresli: Evet

Özet

Tuberous sclerosis complex (TSC) is a genetic disorder characterized by the formation of hamartomas in various organ systems. We would like share our experience from 86 patients and the results of rapamycin treatment in seven children with TSC.