IRANIAN JOURNAL OF ALLERGY ASTHMA AND IMMUNOLOGY, vol.8, pp.57-61, 2009 (SCI-Expanded)
Mutations in any of four known NADPH-oxidase components lead to CGD. X-linked CGD (X-CGD) is caused by defects in CYBB, the gene that encodes gp91-phox. Autosomal recessive (AR) CGD is caused by defects in the genes for p47 phox, p22-phox or p67-phox. The aim of this study was to screen the molecular defect in the fetus of an X-CGD carrier mother and postnatal confirmation of the results.