Elevated Hyaluronan Levels in Patients with Rheumatic Mitral Stenosis and Pulmonary Arterial Thromboembolism

KALAY N., ELÇİK D., Savas G., Altın P., Sakalar C., Kaya O., ...Daha Fazla

HEART LUNG AND CIRCULATION, cilt.23, sa.7, ss.649-654, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 7
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.hlc.2014.01.011
  • Dergi Adı: HEART LUNG AND CIRCULATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.649-654
  • Anahtar Kelimeler: Hyaluronan, Rheumatic mitral stenosis, Pulmonary arterial thromboembolism, Pulmonary arterial hypertension, Percutaneous mitral balloon valvuloplasty, MATRIX-METALLOPROTEINASE INHIBITION, EXTRACELLULAR-MATRIX, VASCULAR-RESISTANCE, COMMISSUROTOMY, HYPERTENSION, ACTIVATION, ACID
  • Erciyes Üniversitesi Adresli: Evet

Özet

Introduction: The role of hyaluronan (HA) was previously demonstrated in patients with idiopathic pulmonary arterial hypertension (PAH). Mitral stenosis (MS) and pulmonary arterial thromboembolism (PTE) are important health problems that can cause pulmonovascular pathology. Pulmonary arterial hypertension develops especially in untreated patients with severe MS and most of patients with PTE. However, there is no data about HA levels in patients with MS and PTE. In this study, we investigated HA levels in patients with rheumatic MS and PTE.