The effects of N-acetylcysteine on cisplatin induced cardiotoxicity

Gunturk, Ee; Yucel, B; Gunturk, İnayet; Yazici, CEVAT; Yay, ARZU; Kose, SEMA

doi:10.4149/bll_2019_068

The effects of N-acetylcysteine on cisplatin induced cardiotoxicity

Gunturk E., Yucel B., Gunturk İ., Yazici C., Yay A. H., Kose K.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.120, sa.6, ss.423-428, 2019 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 120 Sayı: 6
Basım Tarihi: 2019
Doi Numarası: 10.4149/bll_2019_068
Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.423-428
Anahtar Kelimeler: rats, cisplatin, oxidative stress, cardiotoxicity, N-acetylcysteine
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Erciyes Üniversitesi Adresli: Evet

Özet

OBJECTIVES: Recent studies reported that oxidative stress is an important mechanism that contributes to cisplatin induced cardiotoxicity. In the present study, the effects of N-acetylcysteine (NAC), which is an antioxidant, on cisplatin induced cardiotoxicity were investigated in a rat model.