Comparison of the effectiveness of rapamycin and gabapentin treatments on sciatic nerve injury-induced in rats

Canpolat M., Çolpak H. A., Günay Canpolat D., Önder G. Ö., Yetkin M. F., Yay A. H., ...Daha Fazla

Erciyes Medical Journal, cilt.27, sa.2, ss.95-112, 2021 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.14744/etd.2021.87405
  • Dergi Adı: Erciyes Medical Journal
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.95-112
  • Anahtar Kelimeler: Gabapentin, nerve damage, rapamycin, regeneration, NEUROPATHIC PAIN, FUNCTIONAL RECOVERY, REGENERATION, MYELINATION, AUTOPHAGY, EXPRESSION, PROMOTES, PROTEIN
  • Erciyes Üniversitesi Adresli: Evet

Özet

Objective: The purpose of this study was to compare the therapeutic effects of gabapentin (GBP) and different doses of rapamycin (RAPA) in an induced sciatic nerve (SN)-injury rat model.