EURASIAN JOURNAL OF MEDICINE, vol.51, no.2, pp.177-185, 2019 (ESCI)
Article / Article
EURASIAN JOURNAL OF MEDICINE
Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
NSCLC, EGFR, mutation, mRNA, protein, Turkey, GROWTH-FACTOR RECEPTOR, KINASE DOMAIN MUTATIONS, GENE COPY NUMBER, GEFITINIB SENSITIVITY, ACTIVATING MUTATIONS, CLINICOPATHOLOGICAL FEATURES, PROTEIN EXPRESSION, AMPLIFICATION, SURVIVAL, PREDICTORS
Erciyes University Affiliated:
Objective: In this study, we investigated the frequency of Epidermal growth factor receptor (EGFR) gene mutations, the level of EGFR mRNA and protein expressions in Turkish population for indicating substantial differences in the frequency of EGFR mutations, EGFR amplification and EGFR protein expression between populations and the effect of these parameters in response to EGFR tyrosine kinase inhibitors.