A detailed and comparative work for retinal vessel segmentation based on the most effective heuristic approaches

Çetinkaya M. B., Duran H.

BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK, vol.66, no.2, pp.181-200, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 66 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.1515/bmt-2020-0089
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Biotechnology Research Abstracts, EMBASE, INSPEC, MEDLINE
  • Page Numbers: pp.181-200
  • Keywords: artificial bee colony algorithm, differential evolution algorithm, firefly algorithm, grey wolf optimization algorithm, harmony search algorithm, particle swarm optimization algorithm, retinal vessel segmentation, teaching learning based optimization algorithm, DIABETIC-RETINOPATHY, MATCHED-FILTER, BLOOD-VESSELS, IMAGES, EXTRACTION, OPTIMIZATION, ALGORITHM, LEVEL
  • Erciyes University Affiliated: Yes


Computer based imaging and analysis techniques are frequently used for the diagnosis and treatment of retinal diseases. Although retinal images are of high resolution, the contrast of the retinal blood vessels is usually very close to the background of the retinal image. The detection of the retinal blood vessels with low contrast or with contrast close to the background of the retinal image is too difficult. Therefore, improving algorithms which can successfully distinguish retinal blood vessels from the retinal image has become an important area of research. In this work, clustering based heuristic artificial bee colony, particle swarm optimization, differential evolution, teaching learning based optimization, grey wolf optimization, firefly and harmony search algorithms were applied for accurate segmentation of retinal vessels and their performances were compared in terms of convergence speed, mean squared error, standard deviation, sensitivity, specificity. accuracy and precision. From the simulation results it is seen that the performance of the algorithms in terms of convergence speed and mean squared error is close to each other. It is observed from the statistical analyses that the algorithms show stable behavior and also the vessel and the background pixels of the retinal image can successfully be clustered by the heuristic algorithms.