The assessment of oxidative stress on patients with chronic renal failure at different stages and on dialysis patients receiving different hypertensive treatment

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Atıf İçin Kopyala

Günal S., Üstündaǧ B., Günal A. I.

Indian Journal of Clinical Biochemistry, cilt.28, ss.390-395, 2013 (Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 28
• Basım Tarihi: 2013
• Doi Numarası: 10.1007/s12291-013-0316-1
• Dergi Adı: Indian Journal of Clinical Biochemistry
• Derginin Tarandığı İndeksler: Scopus
• Sayfa Sayıları: ss.390-395
• Erciyes Üniversitesi Adresli: Evet

Özet

The aim of this study is to evaluate the oxidative

stress in predialysis, hemodialysis (HD) and peritoneal dialysis

patients and to test the effects of antihypertensive drugs

and volume control on oxidative stress parameters. The study

was composed of five groups as follows: control group

(n = 30), predialysis group (n = 30), peritoneal dialysis

group (n = 30), hemodialysis group, (normotensive with

strict volume control, n = 30), hemodialysis group (normotensive

with medication, n = 30). Plasma malondialdehyde

(MDA), erythrocyte superoxide dismutase (SOD), catalase

(CAT), glutathione peroxidase (GSHPx) and routine biochemical

parameters were studied in all patients. Hemodialysis

patients with strict volume control (HDvc) had lower

levels of MDA than other patient groups (p\0.001), and

CAT, SOD values had highest level other patient groups

(p\0.001). The treatment of hypertensionwith strict volume

control in chronic renal failure patients causes less damage to

the antioxidant capacity.