Effect of propylthiouracil on adenosine deaminase activity and thyroid function in patients with psoriasis

Kose, SEMA; Utaş, Serap; Yazici, CEVAT; Akdas, Ahmet; Kelestimur, F

doi:10.1046/j.1365-2133.2001.04221.x

Effect of propylthiouracil on adenosine deaminase activity and thyroid function in patients with psoriasis

Kose K., Utaş S., Yazici C., Akdas A., Kelestimur F.

BRITISH JOURNAL OF DERMATOLOGY, cilt.144, sa.6, ss.1121-1126, 2001 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 144 Sayı: 6
Basım Tarihi: 2001
Doi Numarası: 10.1046/j.1365-2133.2001.04221.x
Dergi Adı: BRITISH JOURNAL OF DERMATOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1121-1126
Anahtar Kelimeler: adenosine deaminase, propylthiouracil, psoriasis, thyroid function
Erciyes Üniversitesi Adresli: Evet

Özet

Background T-cell activation has been implicated in the pathogenesis of psoriasis; adenosine deaminase (ADA) activity has been considered as a marker of T-cell activation. The antithyroid drug propylthiouracil (PTU) has recently been shown to have beneficial effects on psoriatic lesions, probably by acting on the immune system.