Pyrazinamide-Induced Anaphylaxis: Diagnosed by Skin Test and Successful Desensitization

Bavbek S., Yilmaz I., Aydin O., Ozdemir S. K.

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, cilt.157, sa.2, ss.209-212, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 157 Sayı: 2
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1159/000327537
  • Dergi Adı: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.209-212
  • Anahtar Kelimeler: Anaphylaxis, Pyrazinamide, Prick test, Desensitization, GENERAL-CONSIDERATIONS, PATIENT
  • Erciyes Üniversitesi Adresli: Evet

Özet

Pyrazinamide (PZA), an antituberculosis drug, may cause hypersensitivity reactions. Here, we report a case of anaphylaxis secondary to a PZA administration for tuberculosis pleuritis. To the best of our knowledge, this is the first reported case of strongly possible IgE-mediated, PZA-induced anaphylaxis proved by skin prick test and oral provocation/desensitization. Copyright (C) 2011 S. Karger AG, Basel