Evaluation of the relationship between disease severity and the leptin, adiponectin, and chemerin levels in overweight and obese COVID-19 patients
ANNALS OF CLINICAL AND ANALYTICAL MEDICINE, cilt.15, sa.5, ss.329-333, 2024 (ESCI)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 15 Sayı: 5
- Basım Tarihi: 2024
- Doi Numarası: 10.4328/acam.22078
- Dergi Adı: ANNALS OF CLINICAL AND ANALYTICAL MEDICINE
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
- Sayfa Sayıları: ss.329-333
- Anahtar Kelimeler: COVID-19, Leptin, Adiponectin, Chemerin, Obesity
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Erciyes Üniversitesi Adresli: Evet
Özet
Aim: Overweight and obesity are substantial risk factors in the severity of COVID-19 disease. This study aimed to assess the relationship between the disease severity and leptin, adiponectin, and chemerin levels in overweight and obese COVID-19 patients. Material and Methods: The study involved 60 COVID-19 patients (patient group) and 30 healthy controls with BMI >= 25. The patient group was split into two subgroups based on disease severity (30 mild/moderate and 30 severe/critical patients). The levels of leptin, adiponectin, and chemerin in plasma were determined using the ELISA technique. Results: Our study revealed that leptin levels were considerably increased in both groups of COVID-19 patients compared to the healthy controls, while chemerin levels were decreased. In adiponectin levels, there was no statistically significant difference between the groups. Discussion: Plasma leptin and chemerin levels are associated with the progression and/or severity of disease in overweight and obese COVID-19 patients.